With the Cognitive Neuroendocrinology Lab at the Max Planck Institute for Human Cognitive and Brain Sciences, I helped respond to the reviewers of Biological Psychiatry and resubmit the journal article on the Serotonin Transporter (5-HTT) binding changes in the Pre-menstrual Dysphoric Disorder.
- I did Volumetric-based Morphometry on MRI to check for the grey-matter volume changes in PFC, Midbrain and other subcortical regions.
- Created an illustration to prove the Partial volume effects of PET on MRI in the mid-brain
- For an across-the menstrual cycle longitudinal study, I did the exploratory statistical analysis of the 5-HTT PET map differences in the subcortical regions of Amygdala, ACC, Thalamus, Hippocampus, Dorsal Caudate, Dorsal Putamen and Ventral Striatum of the Healthy vs PMDD.
Illustration of Partial Volume Effects of the Serotonin Transporter Bindings in the midbrain using using FSLeyes
BoxPlots showing 5-HTT Non-displaceable Binding Potential across Menstrual Cycle (Healthy vs PMDD)
More details on the poster below:
PublicationS
Julia Sacher, Rachel G Zsido, Claudia Barth, Franziska Zientek, Michael Rullmann, Julia Luthardt, Marianne Patt, Georg A Becker, Pablo Rusjan, A Veronica Witte, Ralf Regenthal, Abhay Koushik, Juergen Kratzsch, Beate Decker, Petra Jogschies, Arno Villringer, Swen Hesse, Osama Sabri. Increase in Serotonin Transporter Binding in Patients With Premenstrual Dysphoric Disorder Across the Menstrual Cycle: A Case-Control Longitudinal Neuroreceptor Ligand Positron Emission Tomography Imaging Study.
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